5. From pharmacology to clinical pharmacology.

From physical pharmacy to clinical pharmacology.

Research works on molecular interactions in solutions were carried out at School of Pharmacy, the University of Wisconsin under the direction of Prof. T. Higuchi and at Faculty of Pharmaceutical Sciences, Kyoto University under the direction of Prof. H. Sezaki. Studies on permeation of drugs through polymer membranes were carried out at Faculty of Pharmacy and Pharmaceutical Sciences, Universit...

Biochemical and clinical pharmacology of 5-fluorouracil.

The cellular and clinical pharmacology of fluoropyrimidines is characterized by marked interpatient variability in tumor response and patient tolerance. Understanding the metabolic pathways followed by 5-fluorouracil (5-FU) has led to new strategies to optimize therapy with these important agents. The "fluoropyrimidine phenotype" of tumor cells can be used to determine whether therapy with thes...

Clinical Pharmacology

Clinical Pharmacology

Clinical Pharmacology